Human F3/TF Antibody Pair Set (E-KAB-0468)
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For research use only.
| Background |
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades , and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades , which circulate as nonfunctional precursors , this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular , transmembrane , and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.
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| Synonyms |
F3, CD142, TF, TFA, coagulation factor III, tissue factor
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human F3/TF in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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